Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor Utilized in the remedy of several myeloma. Its synthesis or research is essential for ensuring the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-10-one): A vital compound during the synthesis of imatinib, a drug that targets precise sorts of cancer, which include Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the output approach and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is made use of to deal with breast cancer, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): 17-(3-pyridinyl)- This compound is associated with the synthesis of adamantane derivatives, which have a variety of apps, together with antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, which can be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle kind 2 diabetic issues by N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide inhibiting sodium-glucose co-transporter 2 (SGLT2).